Androgen Excess Or Low Estrogen

Category: generalpediatrics-Adolescent Care

Findings: adolescent female with pubic hair but no breast development

Question: What hormone state can cause this?


Anorexia

Category: generalpediatrics-Adolescent Care

Findings: amenorrhea, hypothermia, orthostatic hypotension, hypokalemia, bradycardia, prolonged QT, ST depression

Notes: Beware hypophosphatemia from refeeding syndrome

Question: What eating disorder is associated with these findings?


Bone Age Films

Category: generalpediatrics-Adolescent Care

Findings: breast development before age 8

Notes: Ok to observe if bone age films are within 1-2 years of chronologic age

Question: What do you order if an adolescent female has the following?


Chlamydia Trachomatis

Category: generalpediatrics-Adolescent Care

Findings: most prevalent bacterial STD

Question: Which organism has this characteristic?


Chlamydia Trachomatis And Neisseria Gonorrhea

Category: generalpediatrics-Adolescent Care

Findings: for which requires annual screening for sexually active females younger than 25 years of age, usually minimally symptomatic, may lead to pelvic inflammatory disease if untreated

Question: Which organisms are associated with these findings?


Congenital Adrenal Hyperplasia

Category: generalpediatrics-Adolescent Care

Findings: premature closure of growth plates, accelerated growth but lower final height, hyperandrogenism


Constitutional Growth Delay

Category: generalpediatrics-Adolescent Care

Findings: delayed bone age, delayed puberty, family history of condition

Notes: Patient should eventually reach normal adult height


Desensitization To Penicillin

Category: generalpediatrics-Adolescent Care

Findings: pregnant woman with syphilis and history of anaphylaxis to penicillin

Notes: Doxycycline not safe for fetus as it may affect skeletal growth and teeth abnormalities

Question: What do you do in this case?


Exercise-induced Amenorrhea

Category: generalpediatrics-Adolescent Care

Findings: athlete, delayed puberty, low LH and FSH, no menstruation

Question: What fits these findings?


Fibroadenoma

Category: generalpediatrics-Adolescent Care

Findings: worsened with oral contraceptives, unilateral, most common solid breast mass in adolescent female, rubbery

Notes: Obtain ultrasound for breast abnormalities in adolescents. Observe if asymptomatic and less than 3 cm. Refer for excisional biopsy if persistent, symptomatic, or larger.

Question: Which disease is associated with these findings?


GnRH Analogue

Category: generalpediatrics-Adolescent Care

Findings: elevated LH and FSH, tunnel vision

Notes: Central precocious puberty is evidenced by neurological symptoms as well as elevated central hormones

Question: What class of medication do you use to treatment a disease with the following findings?


Growth Hormone Deficiency

Category: generalpediatrics-Adolescent Care

Findings: small penis or clitoris, hypoglycemia, seizures, decelerating growth curve


HCG

Category: generalpediatrics-Adolescent Care

Findings: amenorrhea

Notes: If hCG is negative, try a progesterone challenge. If positive and patient bleeds, get a LH level and look for PCOS. A low LH may indicate prolactinoma or hypothyroidism. If progesterone challenge is negative, get a FSH to look for deficiencies in estrogen production. High FSH may indicate ovarian failure and Turner's while low FSH could indicate a prolactinoma or other central issue.

Question: What lab should you order for the following symptom


Hydrocele

Category: generalpediatrics-Adolescent Care

Findings: mass superior and anterior to testes, changes position with position and valsalva, resolves by one year old, painless

Notes: Also transluminates

Question: What issue is associated with these findings?


Inguinal Hernia

Category: generalpediatrics-Adolescent Care

Findings: painful scrotal mass that changes with position, does not transilluminate

Notes: Does not transilluminate

Question: Which disease is associated with these findings?


Klebsiella Granulomatis

Category: generalpediatrics-Adolescent Care

Findings: intracellular gram-negative bacterium, painless friable beefy-red ulcerative lesion, no regional lymphadenopathy

Question: Which organism is associated with these findings?


Long Acting Reversible Contraceptives (LARC)

Category: generalpediatrics-Adolescent Care

Findings: 1st line recommended birth control in teenagers

Notes: Includes subdermal progesterone implants and IUDs

Question: Question


Marijuana

Category: generalpediatrics-Adolescent Care

Findings: gynecomastia, galactorrhea

Question: Use of what substance can cause these issues?


Obesity

Category: generalpediatrics-Adolescent Care

Findings: tall stature, advanced bone age, high caloric intake


Polycystic Ovarian Syndrome (PCOS)

Category: generalpediatrics-Adolescent Care

Findings: irregular menses, excessive hair, insulin resistance, acne

Notes: LH to FSH ratio is greater than 2


Primary Dysmenorrhea

Category: generalpediatrics-Adolescent Care

Findings: abdominal pain and cramping before or during menstruation, absence of other disease

Notes: Treat with NSAIDs or COX inhibitors. Take as soon as possible, ideally a few days before predicted onset of pain. Caused by excess prostaglandins.

Question: Which disease is associated with these findings?


Steroids

Category: generalpediatrics-Adolescent Care

Findings: liver dysfunction, high LDL, low HDL, hypertension, labile mood

Notes: Males will have acne and gynecomastia. Girls with have hirsutism and deeper voice.

Question: Use of which substance is associated with these findings?


Tanner Stage 2

Category: generalpediatrics-Adolescent Care

Findings: breast bud, coarse hair or sparse curly hair only along labia, palpable areola

Question: What tanner stage does the following occur?


Tanner Stage 3

Category: generalpediatrics-Adolescent Care

Findings: curly hair at pubis, elevation of breast contour, acne, axillary hair

Question: Which tanner stage would you see with the following in a female?


Tanner Stage 4

Category: generalpediatrics-Adolescent Care

Findings: mound on mound breasts, enlarged areola, dense hair not at thighs, menses

Question: At which tanner stage do females achieve the following?


Testicular Cancer

Category: generalpediatrics-Adolescent Care

Findings: painless scrotal mass, elevated hCG or AFP

Notes: Obtain scrotal ultrasound and CT abdomen for staging.


Testicular Torsion

Category: generalpediatrics-Adolescent Care

Findings: nausea, severe unilateral pain, swollen and tender left testicle, absent cremasteric reflex

Notes: Needs urgent urologic evaluation as this is surgical emergency. Ultrasound would show decreased perfusion on affected side. Needs immediate surgical detorsion and fixation of both testicles.

Question: Which disease is associated with these findings?


Torsion Of Appendix Testes

Category: generalpediatrics-Adolescent Care

Findings: blue dot sign, painful

Notes: Treated by NSAIDs


Varicocele

Category: generalpediatrics-Adolescent Care

Findings: dilated scrotal veins, increases with valsalva

Notes: Usually left sided because of spermatic vein connection to left renal vein perpendicularly. Right sided may indicated issue with IVC. If painful or does not grow or even atrophy, will need surgery. Look for 2 mL or more difference between testicles.

Question: Which issue is associated with these findings?